Thirumala-Devi Kanneganti Selected Research

Inflammation (Inflammations)

2/2024	NINJ1 mediates inflammatory cell death, PANoptosis, and lethality during infection conditions and heat stress.
6/2023	Whole-genome CRISPR screen identifies RAVER1 as a key regulator of RIPK1-mediated inflammatory cell death, PANoptosis.
1/2023	Inflammasome signaling in colorectal cancer.
1/2023	ADAR1 and ZBP1 in innate immunity, cell death, and disease.
1/2023	NLRP12-PANoptosome activates PANoptosis and pathology in response to heme and PAMPs.
1/2023	Immune regulator IRF1 contributes to ZBP1-, AIM2-, RIPK1-, and NLRP12-PANoptosome activation and inflammatory cell death (PANoptosis).
1/2023	Methotrexate suppresses psoriatic skin inflammation by inhibiting muropeptide transporter SLC46A2 activity.
12/2022	Humans pIKK-up NLRP3 to skip NEK7.
11/2022	PANoptosis: A Unique Innate Immune Inflammatory Cell Death Modality.
10/2022	Molecular mechanism of RIPK1 and caspase-8 in homeostatic type I interferon production and regulation.

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Thirumala-Devi Kanneganti Research Topics

Disease

74	Infections 01/2024 - 11/2006
71	Inflammation (Inflammations) 02/2024 - 08/2007
28	Neoplasms (Cancer) 10/2023 - 01/2010
14	Carcinogenesis 10/2023 - 10/2010
12	Melanoma (Melanoma, Malignant) 10/2023 - 05/2015
12	Virus Diseases (Viral Diseases) 11/2022 - 12/2006
11	Colitis 01/2023 - 03/2010
8	Colorectal Neoplasms (Colorectal Cancer) 10/2023 - 10/2010
7	Autoimmune Diseases (Autoimmune Disease) 12/2020 - 02/2011
7	Necrosis 10/2017 - 03/2006
6	Sepsis (Septicemia) 01/2021 - 10/2010
6	Bites and Stings (Sting) 01/2020 - 11/2014
6	Fever (Fevers) 01/2020 - 02/2011
5	COVID-19 01/2022 - 11/2020
5	Obesity 01/2021 - 07/2011
5	Osteomyelitis 01/2020 - 01/2014
5	Bacterial Infections (Bacterial Infection) 01/2018 - 06/2007
4	Cytokine Release Syndrome 10/2023 - 11/2020
4	Mycoses (Diseases, Fungus) 01/2022 - 07/2009
4	Communicable Diseases (Infectious Diseases) 12/2021 - 01/2017
4	Atherosclerosis 01/2021 - 07/2011
4	Familial Mediterranean Fever (Periodic Disease) 11/2020 - 02/2017
4	Chronic recurrent multifocal osteomyelitis 01/2020 - 01/2014
4	Skin Diseases (Skin Disease) 11/2019 - 01/2014
4	Multiple Sclerosis 01/2019 - 05/2010
4	Bone Diseases (Bone Disease) 04/2016 - 01/2014
4	Lyme Disease (Disease, Lyme) 01/2016 - 06/2010
3	Psoriasis (Pustulosis Palmaris et Plantaris) 01/2023 - 02/2016
3	Anthrax 11/2022 - 08/2007
3	Coronavirus Infections 01/2022 - 10/2020
3	Metabolic Diseases (Metabolic Disease) 01/2021 - 03/2015
3	Shock 01/2021 - 10/2010
3	Human Influenza (Influenza) 12/2020 - 01/2018
3	Rheumatoid Arthritis 01/2020 - 01/2014
3	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2019 - 01/2015
3	Arthritis (Polyarthritis) 02/2016 - 04/2010
3	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 04/2012 - 05/2010
2	Neurodegenerative Diseases (Neurodegenerative Disease) 10/2022 - 05/2015
2	Pseudomonas Infections 01/2022 - 01/2018
2	Hemophagocytic Lymphohistiocytosis (Hemophagocytic Syndrome) 01/2021 - 11/2020
2	Leukemia 01/2021 - 06/2015
2	Systemic Lupus Erythematosus (Libman-Sacks Disease) 01/2020 - 01/2017
2	Breast Neoplasms (Breast Cancer) 12/2019 - 01/2017
2	Neoplasm Metastasis (Metastasis) 01/2019 - 01/2017

Drug/Important Bio-Agent (IBA)

116	InflammasomesIBA 10/2023 - 12/2006
44	CytokinesIBA 02/2024 - 12/2008
24	Proteins (Proteins, Gene)FDA Link 01/2024 - 08/2006
18	NLR ProteinsIBA 10/2023 - 06/2007
18	Interleukin-18 (Interleukin 18)IBA 12/2020 - 12/2006
12	Caspase 8 (Caspase-8)IBA 06/2023 - 01/2015
11	Phosphotransferases (Kinase)IBA 06/2023 - 01/2012
11	NucleotidesIBA 01/2023 - 06/2006
10	Carrier Proteins (Binding Protein)IBA 01/2023 - 04/2014
9	CaspasesIBA 01/2020 - 12/2006
9	Caspase 1 (ICE Protease)IBA 01/2016 - 12/2008
8	DNA (Deoxyribonucleic Acid)IBA 10/2023 - 05/2015
8	Interferon Type IIBA 10/2022 - 01/2013
7	Antiviral Agents (Antivirals)IBA 10/2022 - 09/2013
6	PyrinIBA 01/2023 - 02/2017
6	InterferonsIBA 11/2022 - 01/2016
6	Pattern Recognition ReceptorsIBA 11/2022 - 06/2006
6	LigandsIBA 01/2022 - 01/2012
5	Z-Form DNA (Z-DNA)IBA 01/2023 - 01/2018
5	Protein Kinases (Protein Kinase)IBA 01/2023 - 05/2013
5	Toll-Like Receptors (Toll-Like Receptor)IBA 11/2022 - 04/2010
5	ChemokinesIBA 01/2022 - 11/2011
5	LipopolysaccharidesIBA 12/2021 - 06/2006
5	Interleukin-6 (Interleukin 6)IBA 01/2018 - 03/2006
5	Interleukin-1 (Interleukin 1)IBA 11/2016 - 11/2012
4	Pathogen-Associated Molecular Pattern MoleculesIBA 01/2023 - 05/2015
4	Dextrans (Dextran)FDA Link 02/2022 - 03/2010
4	sodium sulfate (sodium bisulfate)FDA LinkGeneric 02/2022 - 03/2010
4	Caspase 3 (Caspase-3)IBA 11/2021 - 12/2008
4	Proline (L-Proline)FDA Link 01/2020 - 12/2014
4	Phosphoprotein Phosphatases (Phosphatases, Protein)IBA 01/2020 - 12/2014
4	InterleukinsIBA 11/2018 - 12/2006
3	Adenosine Triphosphate (ATP)IBA 01/2024 - 06/2007
3	VaccinesIBA 10/2023 - 08/2014
3	RNA (Ribonucleic Acid)IBA 11/2022 - 01/2020
3	AzoxymethaneIBA 02/2022 - 10/2010
3	Transcription Factors (Transcription Factor)IBA 02/2022 - 01/2012
3	Caspase 6IBA 12/2021 - 01/2020
3	Cysteine Proteases (Cysteine Protease)IBA 01/2020 - 12/2008
3	Interleukin-33IBA 01/2019 - 12/2016
3	UbiquitinIBA 01/2019 - 08/2006
3	Interleukin-17 (Interleukin 17)IBA 01/2018 - 01/2011
3	FlagellinIBA 01/2018 - 11/2006
3	Leucine (L-Leucine)FDA Link 01/2017 - 05/2015
3	Interleukin-10 (Interleukin 10)IBA 09/2015 - 04/2014
3	Caspase 7IBA 01/2010 - 12/2008
2	Interferon Regulatory Factor-1 (Interferon Regulatory Factor 1)IBA 01/2023 - 01/2020
2	Biomarkers (Surrogate Marker)IBA 12/2022 - 01/2017
2	C-Type Lectins (C-Type Lectin)IBA 11/2022 - 01/2019
2	MannansIBA 12/2021 - 07/2009
2	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 10/2020 - 01/2020
2	cyclic guanosine monophosphate-adenosine monophosphateIBA 01/2020 - 01/2018
2	Interleukin-4 (Interleukin 4)IBA 01/2020 - 02/2015
2	sharpinIBA 01/2019 - 11/2016

Therapy/Procedure

11	Therapeutics 12/2022 - 04/2010
3	Immunotherapy 01/2021 - 04/2010